Healthcare · Rankings

Best US Cities for Pharmacists

Top US cities for Pharmacists ranked by estimated median salary, with cost-of-living-adjusted earning power.

Top 10 cities by salary
#CityEstimated salaryCost mult.vs national
1San Francisco, CA$185,6001.45×+$57,600
2Oakland, CA$172,8001.35×+$44,800
3New York City, NY$169,0001.32×+$41,000
4Honolulu, HI$166,4001.30×+$38,400
5Irvine, CA$166,4001.30×+$38,400
6Los Angeles, CA$156,2001.22×+$28,200
7Boston, MA$156,2001.22×+$28,200
8San Diego, CA$154,9001.21×+$26,900
9Yonkers, NY$153,6001.20×+$25,600
10Anchorage, AK$153,6001.20×+$25,600
All 50 cities, ranked
#CitySalaryHourly
1San Francisco, CA$185,600$89/hr
2Oakland, CA$172,800$83/hr
3New York City, NY$169,000$81/hr
4Honolulu, HI$166,400$80/hr
5Irvine, CA$166,400$80/hr
6Los Angeles, CA$156,200$75/hr
7Boston, MA$156,200$75/hr
8San Diego, CA$154,900$74/hr
9Yonkers, NY$153,600$74/hr
10Anchorage, AK$153,600$74/hr
11Seattle, WA$151,000$73/hr
12Long Beach, CA$151,000$73/hr
13Anaheim, CA$151,000$73/hr
14Scottsdale, AZ$151,000$73/hr
15Chula Vista, CA$147,200$71/hr
16Miami, FL$143,400$69/hr
17Portland, OR$140,800$68/hr
18Newark, NJ$140,800$68/hr
19Sacramento, CA$140,800$68/hr
20Riverside, CA$140,800$68/hr
21Denver, CO$138,200$66/hr
22Chicago, IL$134,400$65/hr
23Austin, TX$134,400$65/hr
24Baltimore, MD$134,400$65/hr
25Stockton, CA$134,400$65/hr
26Aurora, CO$134,400$65/hr
27Hialeah, FL$134,400$65/hr
28Frisco, TX$134,400$65/hr
29Las Vegas, NV$133,100$64/hr
30Minneapolis, MN$133,100$64/hr
31Plano, TX$133,100$64/hr
32Chandler, AZ$133,100$64/hr
33Phoenix, AZ$130,600$63/hr
34Philadelphia, PA$130,600$63/hr
35Atlanta, GA$130,600$63/hr
36Tampa, FL$130,600$63/hr
37Henderson, NV$130,600$63/hr
38Reno, NV$130,600$63/hr
39Gilbert, AZ$130,600$63/hr
40Charleston, SC$130,600$63/hr
41Salt Lake City, UT$130,600$63/hr
42Orlando, FL$129,300$62/hr
43Wilmington, DE$128,000$62/hr
44Raleigh, NC$128,000$62/hr
45Virginia Beach, VA$128,000$62/hr
46St. Paul, MN$128,000$62/hr
47Chesapeake, VA$128,000$62/hr
48North Las Vegas, NV$128,000$62/hr
49Boise, ID$128,000$62/hr
50Fresno, CA$128,000$62/hr
51Worcester, MA$128,000$62/hr
52Dallas, TX$126,700$61/hr
53Nashville, TN$126,700$61/hr
54Colorado Springs, CO$126,700$61/hr
55Bakersfield, CA$126,700$61/hr
56St. Petersburg, FL$126,700$61/hr
57Madison, WI$126,700$61/hr
58Norfolk, VA$125,400$60/hr
59Jacksonville, FL$124,200$60/hr
60Charlotte, NC$124,200$60/hr
61Mesa, AZ$124,200$60/hr
62Houston, TX$122,900$59/hr
63Fort Worth, TX$122,900$59/hr
64Tucson, AZ$122,900$59/hr
65Glendale, AZ$122,900$59/hr
66Garland, TX$122,900$59/hr
67Spokane, WA$122,900$59/hr
68Pittsburgh, PA$121,600$58/hr
69Arlington, TX$121,600$58/hr
70Tallahassee, FL$121,600$58/hr
71Milwaukee, WI$120,300$58/hr
72Albuquerque, NM$120,300$58/hr
73New Orleans, LA$120,300$58/hr
74San Antonio, TX$119,000$57/hr
75Grand Rapids, MI$119,000$57/hr
76Columbus, OH$117,800$57/hr
77Detroit, MI$117,800$57/hr
78Cincinnati, OH$117,800$57/hr
79Kansas City, MO$117,800$57/hr
80Lexington, KY$117,800$57/hr
81Corpus Christi, TX$117,800$57/hr
82Buffalo, NY$117,800$57/hr
83Greensboro, NC$117,800$57/hr
84Knoxville, TN$117,800$57/hr
85El Paso, TX$116,500$56/hr
86Cleveland, OH$116,500$56/hr
87St. Louis, MO$116,500$56/hr
88Winston-Salem, NC$116,500$56/hr
89Indianapolis, IN$115,200$55/hr
90Louisville, KY$115,200$55/hr
91Omaha, NE$115,200$55/hr
92Memphis, TN$113,900$55/hr
93Oklahoma City, OK$113,900$55/hr
94Lincoln, NE$113,900$55/hr
95Birmingham, AL$112,600$54/hr
96Toledo, OH$112,600$54/hr
97Lubbock, TX$112,600$54/hr
98Wichita, KS$110,100$53/hr
99Fort Wayne, IN$110,100$53/hr
100Mobile, AL$110,100$53/hr

Why pay varies for Pharmacists by city

The estimated median Pharmacist salary varies from $110,100 in Mobile to $185,600 in San Francisco — a 69% range. The drivers:

  • Cost of living: SF Bay, NYC, Honolulu, Boston cost 20-45% more than US average. Employers compete for talent by paying proportionally more.
  • Employer concentration: tech metros (SF, Seattle, Austin, NYC) pay tech roles much more than general-market cities. Healthcare hubs (Boston, NYC) similar effect for medical roles.
  • State and local taxes: TX, FL, NV, WA, AK have no state income tax — net pay is effectively higher. NYC, Philly, Detroit have local taxes that reduce take-home.
  • Industry density: a Pharmacist at a top-tier employer in a major metro can out-earn the local median by 30-50%.

Highest-paying ≠ best earning power

San Francisco and New York lead nominal pay rankings for most jobs. But housing in SF averages $4,500+/month for a 1-bedroom; same in NYC $3,500-4,500. After housing, transit, and taxes, a Pharmacist earning $150K in SF often takes home less spendable income than one earning $100K in Austin or Raleigh.

For real-world earning power, weight salaries against cost of living. Use our cost of living comparison tool to see what specific city pairs translate to.

Pharmacists and remote work

Post-2020, many employers offer location-independent healthcare roles. Pay policies vary:

  • Same nationwide (rare): same salary regardless of where you live. Best for low-COL areas.
  • Tier-based (most common): 3-4 pay tiers based on metro cost. SF gets tier 1, mid-tier metros tier 2, low-COL tier 3.
  • Location-of-employer: pay matches the city the company is HQ'd in.
  • Local-only: must live within commuting distance regardless of remote status.

Always confirm with the employer before relocating expecting their salary to follow you. The right strategy: live in a low-COL city, work for a high-COL-tier employer (if they allow it).

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Frequently Asked Questions

What's the highest-paying city for a Pharmacist?
Based on our cost-of-living-adjusted estimates, San Francisco, CA is the highest-paying city for Pharmacists with an estimated median of $185,600/year. Major metros (SF Bay, NYC, Boston) tend to top the list — they pay more but also cost much more to live in.
Why does pay vary so much by city?
Three main factors: (1) cost of living — employers pay more where housing and services cost more; (2) employer concentration — tech-heavy cities pay tech roles more; (3) state and local taxes — no-state-tax states (TX, FL, NV) effectively pay more after taxes. Use our individual Pharmacist salary by city pages for take-home math.
Is the highest-paying city actually the best for me?
Not necessarily. SF pays the most for many roles but housing alone can eat 40-50% of net income. The "adjusted earning power" column accounts for this — what salary buys after cost of living. Lower-COL cities like Austin or Raleigh sometimes win on adjusted basis despite lower nominal pay.
How accurate are these salary estimates?
These are population-level estimates based on US BLS national medians × city cost-of-living multipliers from BEA Regional Price Parities. Real salaries vary 30%+ within a metro depending on employer, role specifics, and experience. Cross-reference with Glassdoor, Levels.fyi, salary.com for your specific situation.
What about remote work?
Many employers now base pay on cost of living — a remote Pharmacist living in Tucson but employed by a Bay Area company might earn close to local Tucson rates. Check the employer's policy. Some pay the same nationwide; many adjust by location.