Healthcare · Rankings

Best US Cities for Registered Nurses

Top US cities for Registered Nurses ranked by estimated median salary, with cost-of-living-adjusted earning power.

Top 10 cities by salary
#CityEstimated salaryCost mult.vs national
1San Francisco, CA$124,7001.45×+$38,700
2Oakland, CA$116,1001.35×+$30,100
3New York City, NY$113,5001.32×+$27,500
4Honolulu, HI$111,8001.30×+$25,800
5Irvine, CA$111,8001.30×+$25,800
6Los Angeles, CA$104,9001.22×+$18,900
7Boston, MA$104,9001.22×+$18,900
8San Diego, CA$104,1001.21×+$18,100
9Yonkers, NY$103,2001.20×+$17,200
10Anchorage, AK$103,2001.20×+$17,200
All 50 cities, ranked
#CitySalaryHourly
1San Francisco, CA$124,700$60/hr
2Oakland, CA$116,100$56/hr
3New York City, NY$113,500$55/hr
4Honolulu, HI$111,800$54/hr
5Irvine, CA$111,800$54/hr
6Los Angeles, CA$104,900$50/hr
7Boston, MA$104,900$50/hr
8San Diego, CA$104,100$50/hr
9Yonkers, NY$103,200$50/hr
10Anchorage, AK$103,200$50/hr
11Seattle, WA$101,500$49/hr
12Long Beach, CA$101,500$49/hr
13Anaheim, CA$101,500$49/hr
14Scottsdale, AZ$101,500$49/hr
15Chula Vista, CA$98,900$48/hr
16Miami, FL$96,300$46/hr
17Portland, OR$94,600$45/hr
18Newark, NJ$94,600$45/hr
19Sacramento, CA$94,600$45/hr
20Riverside, CA$94,600$45/hr
21Denver, CO$92,900$45/hr
22Chicago, IL$90,300$43/hr
23Austin, TX$90,300$43/hr
24Baltimore, MD$90,300$43/hr
25Stockton, CA$90,300$43/hr
26Aurora, CO$90,300$43/hr
27Hialeah, FL$90,300$43/hr
28Frisco, TX$90,300$43/hr
29Las Vegas, NV$89,400$43/hr
30Minneapolis, MN$89,400$43/hr
31Plano, TX$89,400$43/hr
32Chandler, AZ$89,400$43/hr
33Phoenix, AZ$87,700$42/hr
34Philadelphia, PA$87,700$42/hr
35Atlanta, GA$87,700$42/hr
36Tampa, FL$87,700$42/hr
37Henderson, NV$87,700$42/hr
38Reno, NV$87,700$42/hr
39Gilbert, AZ$87,700$42/hr
40Charleston, SC$87,700$42/hr
41Salt Lake City, UT$87,700$42/hr
42Orlando, FL$86,900$42/hr
43Wilmington, DE$86,000$41/hr
44Raleigh, NC$86,000$41/hr
45Virginia Beach, VA$86,000$41/hr
46St. Paul, MN$86,000$41/hr
47Chesapeake, VA$86,000$41/hr
48North Las Vegas, NV$86,000$41/hr
49Boise, ID$86,000$41/hr
50Fresno, CA$86,000$41/hr
51Worcester, MA$86,000$41/hr
52Dallas, TX$85,100$41/hr
53Nashville, TN$85,100$41/hr
54Colorado Springs, CO$85,100$41/hr
55Bakersfield, CA$85,100$41/hr
56St. Petersburg, FL$85,100$41/hr
57Madison, WI$85,100$41/hr
58Norfolk, VA$84,300$41/hr
59Jacksonville, FL$83,400$40/hr
60Charlotte, NC$83,400$40/hr
61Mesa, AZ$83,400$40/hr
62Houston, TX$82,600$40/hr
63Fort Worth, TX$82,600$40/hr
64Tucson, AZ$82,600$40/hr
65Glendale, AZ$82,600$40/hr
66Garland, TX$82,600$40/hr
67Spokane, WA$82,600$40/hr
68Pittsburgh, PA$81,700$39/hr
69Arlington, TX$81,700$39/hr
70Tallahassee, FL$81,700$39/hr
71Milwaukee, WI$80,800$39/hr
72Albuquerque, NM$80,800$39/hr
73New Orleans, LA$80,800$39/hr
74San Antonio, TX$80,000$38/hr
75Grand Rapids, MI$80,000$38/hr
76Columbus, OH$79,100$38/hr
77Detroit, MI$79,100$38/hr
78Cincinnati, OH$79,100$38/hr
79Kansas City, MO$79,100$38/hr
80Lexington, KY$79,100$38/hr
81Corpus Christi, TX$79,100$38/hr
82Buffalo, NY$79,100$38/hr
83Greensboro, NC$79,100$38/hr
84Knoxville, TN$79,100$38/hr
85El Paso, TX$78,300$38/hr
86Cleveland, OH$78,300$38/hr
87St. Louis, MO$78,300$38/hr
88Winston-Salem, NC$78,300$38/hr
89Indianapolis, IN$77,400$37/hr
90Louisville, KY$77,400$37/hr
91Omaha, NE$77,400$37/hr
92Memphis, TN$76,500$37/hr
93Oklahoma City, OK$76,500$37/hr
94Lincoln, NE$76,500$37/hr
95Birmingham, AL$75,700$36/hr
96Toledo, OH$75,700$36/hr
97Lubbock, TX$75,700$36/hr
98Wichita, KS$74,000$36/hr
99Fort Wayne, IN$74,000$36/hr
100Mobile, AL$74,000$36/hr

Why pay varies for Registered Nurses by city

The estimated median Registered Nurse salary varies from $74,000 in Mobile to $124,700 in San Francisco — a 69% range. The drivers:

  • Cost of living: SF Bay, NYC, Honolulu, Boston cost 20-45% more than US average. Employers compete for talent by paying proportionally more.
  • Employer concentration: tech metros (SF, Seattle, Austin, NYC) pay tech roles much more than general-market cities. Healthcare hubs (Boston, NYC) similar effect for medical roles.
  • State and local taxes: TX, FL, NV, WA, AK have no state income tax — net pay is effectively higher. NYC, Philly, Detroit have local taxes that reduce take-home.
  • Industry density: a Registered Nurse at a top-tier employer in a major metro can out-earn the local median by 30-50%.

Highest-paying ≠ best earning power

San Francisco and New York lead nominal pay rankings for most jobs. But housing in SF averages $4,500+/month for a 1-bedroom; same in NYC $3,500-4,500. After housing, transit, and taxes, a Registered Nurse earning $150K in SF often takes home less spendable income than one earning $100K in Austin or Raleigh.

For real-world earning power, weight salaries against cost of living. Use our cost of living comparison tool to see what specific city pairs translate to.

Registered Nurses and remote work

Post-2020, many employers offer location-independent healthcare roles. Pay policies vary:

  • Same nationwide (rare): same salary regardless of where you live. Best for low-COL areas.
  • Tier-based (most common): 3-4 pay tiers based on metro cost. SF gets tier 1, mid-tier metros tier 2, low-COL tier 3.
  • Location-of-employer: pay matches the city the company is HQ'd in.
  • Local-only: must live within commuting distance regardless of remote status.

Always confirm with the employer before relocating expecting their salary to follow you. The right strategy: live in a low-COL city, work for a high-COL-tier employer (if they allow it).

Other Healthcare jobs to compare

Frequently Asked Questions

What's the highest-paying city for a Registered Nurse?
Based on our cost-of-living-adjusted estimates, San Francisco, CA is the highest-paying city for Registered Nurses with an estimated median of $124,700/year. Major metros (SF Bay, NYC, Boston) tend to top the list — they pay more but also cost much more to live in.
Why does pay vary so much by city?
Three main factors: (1) cost of living — employers pay more where housing and services cost more; (2) employer concentration — tech-heavy cities pay tech roles more; (3) state and local taxes — no-state-tax states (TX, FL, NV) effectively pay more after taxes. Use our individual Registered Nurse salary by city pages for take-home math.
Is the highest-paying city actually the best for me?
Not necessarily. SF pays the most for many roles but housing alone can eat 40-50% of net income. The "adjusted earning power" column accounts for this — what salary buys after cost of living. Lower-COL cities like Austin or Raleigh sometimes win on adjusted basis despite lower nominal pay.
How accurate are these salary estimates?
These are population-level estimates based on US BLS national medians × city cost-of-living multipliers from BEA Regional Price Parities. Real salaries vary 30%+ within a metro depending on employer, role specifics, and experience. Cross-reference with Glassdoor, Levels.fyi, salary.com for your specific situation.
What about remote work?
Many employers now base pay on cost of living — a remote Registered Nurse living in Tucson but employed by a Bay Area company might earn close to local Tucson rates. Check the employer's policy. Some pay the same nationwide; many adjust by location.